Thompson was innate around North Bay, Ontario, Canada, and grew higher within Brampton, Ontario. Fallowing graduating from either a York University School of Drama, he became a member of The Children in the Hall. That company's series aired starting 1989 on the CBC in Canada and in HBO in the United States, but moved to CBS for the fourth & fifth seasons.

Openly gay, he became the gay celebrity in a period of the dog of the indicate. Right-known for his monologues when a lisping Buddy Cole, he also acted regularly on The Larry Sanders Show and made numerous guest appearances in more television series including Politically Incorrect, The Late Show, ''Late Night with Conan O'Brien, Train 48 and Star Trek: Voyager as Ambassador Tomin.

Filmography
A second Homosexual Moving picture (2005) My Fabulous Gay Wedding (2005) (TV series) Burnt Toast (2005) (TV) The Pacifier (2005) Stunt C*ocks (2004) Promenade Queen: A Marc Hall Story (2004) (TV) Ham & Cheese (2004) My Baby's Daddy (2004) Cypher Knows Anything! (2003) A Red Sneakers (2003) (TV) Kids in the Hall: Tour of Duty (2002) (V) RoboRoach (2002) (TV series) Tart (2001) More Tales of the City (2001) (mini series) Mickey Blue Eyes (1999) Supplementary Tales of the City (1998) (mini series) Yahoo (1997) Hijacking Hollywood (1997) Kids in the Hall: Brain Candy (1996) The Larry Sanders Show (1992) (TV series) (1995-1998) Extremely 8-1/2 (1993) Millennium (1989) Day Of these (1989) (TV) The Kids in the Hall (1988) (TV series) Hot Paint (1988) (TV) Head Professional (1985) Cheech & Chong's Next Movie (1980)

Other works
Buddy Babylon, A Autobiography of Buddy Cole (by having Paul Bellini) in 1998, the humor novel, ISBN 0-440-50828-2 A Lowest Indicate olympic games'', the 2001 of these-human indicate produced within Toronto